Contents

1. General Considerations
   • Role of molecular imaging at each drug development stage
   • Drug development roadmap through the utilization of molecular imaging / microdose tests
   • Impact of molecular imaging / microdose tests on clinical development
   • Points of survey results
   • A map related to molecular imaging / microdose tests

1. Background
   1. What is molecular imaging?
   2. Background of molecular imaging being utilized for drug development
   3. History of molecular imaging research and development
2. Technologies / Devices Used for Molecular Imaging
   1. PET (Positron Emission Tomography)
   2. SPECT (Single Photon Emission Computed Tomography)
   3. MRI (Magnetic Resonance Imaging)
   4. X-ray Computed Tomography
   5. Fluorescence
   6. Other imaging technologies
   7. List of PET / SPECT / CT/ MRI equipment for animal use available in Japan
   8. Case study of molecular imaging-related product distributors
3. Development of Pharmaceuticals Utilizing Molecular Imaging Technologies
   1. Molecular imaging at a clinical level
   2. Molecular imaging at a preclinical level
   3. Results of the survey on animal tests by Japanese pharmaceutical companies utilizing imaging technologies
   4. Future outlook of drug development utilizing molecular imaging
4. Major Research Institutes / Universities Working On Molecular Imaging
   1. Case study; Public research institutes, universities, and private companies
   2. Results of interviews
5. Venture Firms Working On Molecular Imaging
   1. Venture firms in Japan
   2. Venture firms in the EU/US
6. Microdose Tests and Molecular Imaging
   1. About microdose tests
   2. Movements related to microdose tests in and outside Japan
   3. Companies related to microdose tests in and outside Japan
   4. Results of the survey of Japanese pharmaceutical companies performing microdose tests
   5. Issues to be addressed in microdose tests
   6. Future outlook of microdose tests
7. Topics on Molecular Tests / Microdose Tests
   1. Regulations and guidelines for molecular imaging / microdose tests
   2. National projects
   3. Societies / industrial associations related to molecular imaging
   4. Molecular imaging researchers in Japan